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Job

Vice President/Senior Vice President, Clinical Science

  • Location

    San Jose

  • Sector:

    Life Sciences

  • Job type:

    Permanent

  • Salary:

    $350,000 +

  • Contact:

    Cyrus Nazari

  • Contact email:

    c.nazari@hamlynwilliams.com

  • Salary high:

    0

  • Salary low:

    0

  • Job ref:

    #LI-cn1

  • Published:

    about 2 months ago

  • Expiry date:

    2021-07-16

  • Startdate:

    ASAP

Vice President/Senior Vice President, Clinical Science

Clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit high-value frontier targets in RAS-addicted cancers.  The company’s focus is on RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. 

The Opportunity:

Reporting directly to Head of Clinical Development, the VP/SVP Clinical Science will provide leadership, clinical development strategy, and oversight of clinical science deliverables for clinical programs. Additionally, the VP/SVP Clinical Science will provide supervision and management to Medical Directors and Clinical Scientists.

The VP/SVP Clinical Science will have the following specific responsibilities:

  • Responsible for the delivery of clinical strategy for the pipeline.

  • Standing member of the program governance body.

  • Responsible for protocols and investigator brochures for clinical stage molecules.

  • Develop/manage infrastructure, processes, budget, etc. for the Clinical Science Organization.

  • Hire, develop, and oversee the work of direct/indirect reports within the Clinical Science Organization.

  • Drive protocol development by leading and partnering with a cross-functional team, including Research, Biometrics, Clinical Operations, Development Diagnostics, and Regulatory.

  • Represent clinical with external stakeholders including investigators, key opinion leaders, and investors.

  • Play a leadership role in the design and timely and high-quality implementation of Phase 1-4 clinical studies.

  • Play a leadership in global regulatory submission and registration.

  • Partner with cross-functional groups to map out clinical and regulatory strategies.

  • Collaborate with clinical operations on investigator selection and engagement.

  • Partner with the Research and Development Diagnostics groups to assure alignment of diagnostics strategy including patient selection and development of companion diagnostics.

  • Oversee the review, analysis, and reporting of clinical data in collaboration with biometrics to enable internal decision making and regulatory filings.

Required Experience, Skills, and Education:

  • M.D. (or non-US equivalent) or MD/PhD, board certified.

  • A minimum of 10-15 years of experience in the pharmaceutical/biotech industry or academia, preferably the majority in oncology drug development.

  • A minimum of 5-10 years of leadership and management experience.

  • Extensive experience in protocol design, implementation, and management of global phase 1-4 clinical trials.

  • Direct experience interfacing with regulatory agencies, strong working knowledge and understanding of regulatory requirements for drug development, and preferably approval in more than one key region (ie. US, EU, Japan).

  • Experience networking with key opinion leaders in oncology and more specifically RAS and mTOR signaling pathways highly preferred.

  • Travel required.